Publikationer

Contents
1 Publication Statistics 2
2 Peer-Reviewed Reports of Original Findings 2
2.1 Copenhagen 1971-73 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2
2.2 New York 1973-76 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2
2.3 Copenhagen 1976-86 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2
2.4 Montreal 1986-94 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
2.5 Aarhus 1994-2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6
2.6 Copenhagen 2009- . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
3 Editorials, Perspectives, and Reviews 16
4 Authored or Edited Books and Booklets 17
5 Textbook Chapters 18
6 Review Chapters in Books 19
7 Chapters in Conference Proceedings 19
8 Letters and Comments 22
9 History of Medicine and Obituaries 22

1 PUBLICATION STATISTICS 2
1 Publication Statistics
• 708 publications in Thomson-Reuters Web of Science
• Google scholar citations February 7, 2016: 22096 (since 2011: 6691)
• i10 index: total 284 (since 2011: 151)
• Hirsch index: 75 (since 2011: 39)

2 Peer-Reviewed Reports of Original Findings
2.1 Copenhagen 1971-73
1. Gjedde A, Crone C (1975) Induction processes in blood-brain transfer of ketone bodies during starvation. Am J
Physiol 229: 1165-1169.
2. Gjedde A, Andersson J, Ekl¨of B (1975) Brain uptake of lactate, antipyrine, water and ethanol. Acta Physiol Scand
93: 145-149.
2.2 New York 1973-76
3. Gjedde A, Caronna JJ, Hindfelt B, Plum F (1975) Whole-brain blood flow and oxygen metabolism in the rat during
nitrous oxide anesthesia. Am J Physiol 229: 113-118.
4. Gjedde A, Hindfelt B (1975) Whole-brain blood flow and oxygen metabolism in the rat after halothane anesthesia.
Acta Anaesthesiol Scand 19: 310-315.
5. Gjedde A, de la Monte SM, Caronna JJ (1977) Cerebral blood flow and oxygen consumption in rat, measured with
microspheres or xenon. Acta Physiol Scand 100: 273-281.
6. Gjedde A, Lockwood A, Duffy TE, Plum F (1978) Cerebral blood flow and metabolism in chronically hyperammonemic
rats: Effect of an acute ammonia challenge. Ann Neurol 3: 325-330.
7. Gregoire NM, Gjedde A, Plum F, Duffy TE (1978) Cerebral blood flow and cerebral metabolic rates for oxygen,
glucose, and ketone bodies in new-born dogs. J Neurochem 30: 63-69.
2.3 Copenhagen 1976-86
8. Gjedde A, Gundtoft O, Svane H (1978) Deep sedative hypothermia (in Danish: Dyb sedativ hypotermi). Ugeskr
Læger 140: 1408-1411.
9. Gjedde A, Hansen AJ, Siemkowicz E (1980) Rapid simultaneous determination of regional blood flow and blood-brain
glucose transfer in brain of rat. Acta Physiol Scand 108: 321-330.
10. Gjedde A (1980) Rapid steady-state analysis of blood-brain glucoser transfer in rat. Acta Physiol Scand 108: 331-339.
11. Hansen AJ, Quistorff B, Gjedde A (1980) Relationship between local changes in cortical blood flow and extracellular
K+ during spreading depression. Acta Physiol Scand 109: 1-6.
12. Gjedde SB, Gjedde A (1980) Organ blood flow rates and cardiac output of the BALB/c mouse. Comp Biochem
Physiol 67A: 671-674.
13. Siemkowicz E, Gjedde A (1980) Post-ischemic coma in rat: Effect of different pre-ischemic blood glucose levels on
cerebral metabolic recovery after ischemia. Acta Physiol Scand 110: 225-232.
14. Gjedde A, Rasmussen M (1980) Blood-brain glucose transport in the conscious rat: Comparison of the intravenous
and intracarotid injection methods. J Neurochem 35: 1375-1381.
15. Gjedde A, Rasmussen M (1980) Pentobarbital anesthesia reduces blood-brain glucose transfer in the rat. J Neurochem
35: 1382-1387.
16. Hansen AJ, Gjedde A, Siemkowicz E (1980) Extracellular potassium and blood flow in the post-ischemic rat brain.
Pflugers Arch 389: 1-7.
17. Gjedde A (1981) High- and low-affinity transport of D-glucose from blood to brain. J Neurochem 36: 1463-1471.
18. Gjedde A, Hansen AJ, Quistorff B (1981) Blood-brain glucose transfer in spreading depression. J Neurochem 37:
807-812.
19. Christensen TG, Diemer NH, Laursen H, Gjedde A (1981) Starvation accelerates blood-brain glucose transfer. Acta
Physiol Scand 112: 221-223.
20. Gjedde A, Crone C (1981) Blood-brain glucose transfer: Repression in chronic hyperglycemia. Science 214: 456-457.
21. Lauritzen M, Jørgensen MB, Diemer NH, Gjedde A, Hansen AJ (1982) Persistent oligemia of rat cerebral cortex in
the wake of spreading depression. Ann Neurol 12: 469-474.
2 PEER-REVIEWED REPORTS OF ORIGINAL FINDINGS 3
22. GjeddeA (1982) Calculation of glucose phosphorylation from brain uptake of glucose analogs in vivo: A re-examination.
Brain Res Rev 4: 237-274.
23. Siemkowicz E, Hansen AJ, Gjedde A (1982) Hyperglycemic ischemia of rat brain: The effect of post-ischemic insulin
on metabolic rate. Brain Res 243: 386-390.
24. Gjedde A (1982) The blood-brain barrier is impermeable to metrizamide. Acta Neurol Scand 66: 392-395.
25. Font C, Garcia-Campos M, Hansen AJ, Siemkowicz E, Gjedde A (1982) Constantes de difusion de inositol en cerebro
de ratas. Laboratorio (Granada) 73: 499-506.
26. Gjedde A, Diemer NH (1983) Autoradiographic determination of regional brain glucose content J Cereb Blood Flow
Metab 3: 303-310.
27. Gjedde A, Christensen O (1984) Estimates of Michaelis-Menten constants for the two membranes of the brain endothelium.
J Cereb Blood Flow Metab 4: 241-249.
28. Bech L, Diemer NH, Gjedde A (1984) The effect of metrizamide on regional brain glucose metabolism in the rat. Acta
Neurol Scand 69: 249-253.
29. Gjedde A: (1984) On the measurement of glucose in brain. Neurochem Res 9: 1667-1671.
30. Gjedde A (1984) Blood-brain transport of galactose in experimental galactosemia. With special reference to the
competitive interaction between galactose and glucose. J Neurochem 43: 1654-1662.
31. Wong D, Wagner HN, Dannals RF, Links JM, Frost JJ, Ravert HT, Wilson AA, Rosenbaum AE, Gjedde A, Douglass
KH, Petronis JD, Folstein MF, Toung JKT, Burns HD, Kuhar MJ (1984) Effects of age on dopamine and serotonin
receptors measured by positron tomography in the living human brain. Science 226: 1393-1396.
32. Gjedde A, Diemer NH (1985) A double tracer study of the fine regional blood-brain glucose transfer in the rat by
computer-assisted autoradiography (CAA). J Cereb Blood Flow Metab 5: 163-178.
33. Gjedde A, Wienhard K, Heiss W-D, Kloster G, Diemer NH, Herholz K, Pawlik G: (1985) Comparative regional
analysis of 2-fluorodeoxyglucose and methylglucose uptake in brain of four stroke patients. J Cereb Blood Flow Metab
5: 282-289.
34. Andersen A, Waaben J, Husum B, Voldby B, Bødker A, Hansen AJ, Gjedde A (1985) Non-pulsatile cardiopulmonary
bypass disrupts the flow-metabolism couple in brain. J Thorac Cardiovasc Surg 40: 570-579.
35. Bech L, Diemer NH, Gjedde A (1985) Metabolic effect of topical application of metrizamide to rat brain cortex. Acta
Neurol Scand 72: 427-431.
36. Wong DF, Gjedde A, Wagner HNJr: (1986) Quantification of neuroreceptors in the living human brain. I: Irreversible
binding. J Cereb Blood Flow Metab 6: 137-146.
37. Wong DF, Gjedde A, Wagner HNJr, Dannals RF, Douglass KH, Links JM, Kuhar MJ (1986) Quantification of
neuroreceptors in the living human brain. II: Inhibition studies of receptor density. J Cereb Blood Flow Metab 6:
147-153.
38. Fuglsang A, Lomholt M, Gjedde A (1986) Blood-brain transfer of glucose and glucose analogs in newborn rats. J
Neurochem 46: 1417-1428.
39. Kretzschmar R, Landgraf R, Gjedde A, Ermisch A (1986) Vasopressin binds to microvessels from rat hippocampus.
Brain Res 380: 325-330.
40. Nedergaard M, Gjedde A, Diemer NH (1986) Focal ischemia of the rat brain: Autoradiographic determination of
cerebral glucose utilization, glucose content and blood flow. J Cereb Blood Flow Metab 6: 414-424.
41. Wong DF, Wagner HNJr, Links JM, Kuhar MJ, Gjedde A (1986) Human brain receptor distribution. Science 232:
1269-1271.
42. Wong DF, Wagner HNJr, Tune LE, Dannals RF, Pearlson GD, Links JM, Tamminga CA, Broussole EP, Ravert HT,
Wilson AA, Toung JKT, Malat J, Williams JA, O’Tuama LA, Snyder SH, Kuhar MJ, Gjedde A (1986) Positron
emission tomography reveals elevated D2 dopamine receptors in drug-naive schizophrenics. Science 234: 1558-1563.
43. Reith J, Ermisch A, and Gjedde A (1986) Saturable vasopressin retention in hippocampal endothelium and in non-BBB
brain regions (pineal and pituitary gland s). Wiss. Z. Karl Marx Univ. 36: 87-90.
44. Reith J, Ermisch A, Diemer NH, Gjedde A (1987) Saturable retention of vasopressin by hippocampus vessels in vivo,
associated with inhibition of blood-brain transfer of large neutral amino acids. J Neurochem 49: 1471-1479.
45. Nedergaard M, Gjedde A, Diemer NH (1987) Hyperglycemia protects against neuronal injury around experimental
brain infarcts. Neurol Res 9: 241-244.
2.4 Montreal 1986-94
46. Redies C, Diksic M, Evans AC, Gjedde A, Yamamoto YL (1987) Double-label autoradiographic deoxyglucose method
for sequential measurement of regional cerebral glucose utilization. Neurosci 22: 601-619.
47. Brøndsted HE, Gjedde A (1988) Measuring brain glucose phosphorylation with labeled glucose. Am J Physiol 254:
E443-E448.
2 PEER-REVIEWED REPORTS OF ORIGINAL FINDINGS 4
48. Rahbek Sørensen H, Husum B, Waaben J, Andersen K, Andersen LI, Gefke K, Kaarsen AL, Gjedde A (1988) Brain
microvascular function during cardiopulmonary bypass. J Thorac Cardiovasc Surg 94: 727-732.
49. Redies C, Diksic M, Collier B, Gjedde A, Thompson CJ, Gauthier S, Feindel WH (1988) Influx of a choline analog to
dog brain measured by PET. Synapse 2: 406-411.
50. Waaben J, Husum B, Hansen AJ, Gjedde A (1989) Local cerebral blood flow and glucose utilization during hyperventilation
and adenosine-induced hypotension in the rat. Anesthesiology 70: 299-304.
51. Dyve, SE, Gjedde A, Diksic M, Sherwin A, Hakim AM (1989) In vivo quantification of blood-brain transfer and
binding of (125I)heat, an alpha-1 adrenoceptor antagonist. Synapse 3: 205-212.
52. Waaben J, Husum B, Hansen AJ, Gjedde A (1989) Hypocapnia prevents the decrease in local cerebral metabolism
during isoflurane-induced hypotension. J Neurosurg Anesthesiol 1: 29-34.
53. Hakim AM, Evans AC, Berger L, Kuwabara H, Worsely K, Marchal G, Beil C, Pokrupa R, Diksic M, Meyer E, Gjedde
A, Marrett S (1989) The effect of nimodipine on the evolution of human cerebral infarction studied by PET. J Cereb
Blood Flow Metab 9: 523-534.
54. Redies C, Hoffer LJ, Beil C, Marliss EB, Evans AC, Lariviere F, Marrett S, Meyer E, Diksic M, Gjedde A, Hakim
AM (1989) Generalized decrease in brain glucose metabolism during fasting in humans studied by pet. Am J Physiol
256: E805-E810.
55. Gjedde A, Evans AC (1989) PET studies of domoic acid poisoning in humans: Excitotoxic destruction of brain
glutamatergic pathways, revealed in measurements of glucose metabolism by positron emission tomography. In: Domoic
Acid Toxicity: Canada Diseases Weekly Volume 16S1E, pp. 105-109.
56. Kuwabara H, Evans AC, Gjedde A (1990) Michaelis-Menten constraints improved cerebral glucose metabolism and
regional lumped constant measurements with [18F]fluorodeoxyglucose. J Cereb Blood Flow Metab 10: 180-189.
57. Gjedde A, Kuwabara H, Hakim A (1990) Reduction of functional capillary density in human brain after stroke. J
Cereb Blood Flow Metab 10: 317-316.
58. Teitelbaum JS, Zatorre RJ, Carpenter S, Gendron D, Evans AC, Gjedde A, Cashman NR (1990) Neurological sequelae
of domoic acid intoxication due to ingestion of mussels from Prince Edward Island. N Eng J Med 322: 1781-1787.
59. Brøndsted HE, Reith J, Gjedde A (1990) Regional glucose phosphorylation rate in brain during acute ethanol intoxication.
Acta Neurol Scand 81: 229-231.
60. Brøndsted HE, and Gjedde A (1990) Phosphorylation rate in rat brain during normoglycemia, hypoglycemia, acute
hyperglycemia and in diabetes-prone rats. Acta Neurol Scand 81: 233-236.
61. Reith J, Dyve S, Kuwabara H, Guttman M, Diksic M, Gjedde A (1990) Blood-brain transfer and metabolism of
6-[18F]fluoro-l-dopa. J Cereb Blood Flow Metab 10: 707-719, 1990.
62. Dyve S, Gjedde A (1991) Glucose metabolism of fetal rat brain in utero, measured with labeled deoxyglucose. Acta
Neurol Scand 83: 14-19.
63. Hogan MJ, Gjedde A, Hakim AM (1991) Activity of the dihydorpyridine calcium channels following cerebral ischemia.
Arzneim Forsch/Drug Res 41(I) nr.3a: 332-333.
64. Kuwabara H, Gjedde A (1991) Measurements of glucose phosphorylation with fdg are not affected by dephosphorylation
of fdg-6-phosphate. J Nucl Med 32: 692-698.
65. Gjedde A, Reith J, Dyve S, L´eger G, Guttman M, Diksic M, Evans AC, Kuwabara H (1991) dopa decarboxylase
activity of the living human brain. Proc Nat Acad Sci (USA) 88: 2721-2725.
66. Thompson CJ, Ranger N, Evans AC, Gjedde A (1991) Validation of simultaneous PET emission and transmission
scans. J Nucl Med 32: 154-160.
67. Blomqvist G, Gjedde A, Gutniak M, Grill V, Widen L, Stone-Elander S, Hellstrand E (1991) Facilitated transport
of glucose from blood to brain in man and the effect of moderate hypoglycemia on cerebral glucose utilization. Eur J
Nucl Med 18: 834-837.
68. Gjedde A, Dyve S, Yang Y-J, McHugh M, Pappius M (1991) Bi-Affinity -1 adrenoceptor binding in normal rat brain
in vivo. Synapse 9: 1-6.
69. Hogan MJ, Gjedde A, Hakim AM (1991) In-vivo binding of nimodipine in brain II. Binding kinetics in focal cerebral
ischemia. J Cereb Blood Flow Metab 11: 771-778.
70. Brust P, Baethmann A, Gjedde A, Ermisch A (1991) Atrial natriuretic peptide augments the blood-brain transfer of
water but not leucine and glucose. Brain Res 564: 91-96.
71. Ohta S, Meyer E, Thompson CJ and Gjedde A (1992) Oxygen consumption of the living human brain measured after
a single inhalation of positron emitting oxygen. J Cereb Blood Flow Metab 12: 179-192.
72. Hogan MJ, Gjedde A, Hakim AM (1992) The in-vivo distribution of CGS-19755 within brain in a model of focal
cerebral ischemia. J Neurochem 58: 186-191.
73. Guttman M, L´eger G, Cederbaum JM, Reches A, Woodward W, Evans A, Diksic M, Gjedde A (1992) 3-O-methyldopa
administration does not alter fluorodopa transport into the brain. Ann Neurol 31: 638-643.
2 PEER-REVIEWED REPORTS OF ORIGINAL FINDINGS 5
74. Brust P, Shaya EK, Jeffries KJ, Dannals RF, Ravert HT, Wilson AA, Conti PS, Wagner Jr. HN, Gjedde A, Ermisch
A, Wong DF (1992) Effects of vasopressin on blood-brain transfer of L-[11C]methionine in dogs. J Neurochem 59:
1421-1429.
75. Zatorre R, Evans AC, Meyer E, Gjedde A (1992) Lateralization of phonetic and pitch discrimination in speech
processing. Science 256: 846-849.
76. Spencer D, Robbins R, Naftolin F, Marek K, Vollmer T, Leranth C, Roth R, Price L, Gjedde A, Bunney B, Sass K,
Elsworth J, Kier E, Makuch R, Hoffer P, Redmond D (1992) Unilateral transplantation of human fetal mesencephalic
tissue into the caudate nucleus of patients with Parkinson’s disease. New Engl J Med 327: 1541-1548.
77. Kuwabara H, Cumming P, Reith J, L´eger G, Diksic M, Evans A, Gjedde A (1993) Human striatal L-DOPA decarboxylase
activity estimated in vivo using 6-[18F]fluoro-DOPA and positron emission tomography: Error analysis and
application to normal subjects. J Cereb Blood Flow Metab 13: 43-56.
78. Hoshi H, Kuwabara H, L´eger G, Cumming P, Guttman M, Gjedde A (1993) 6-[18F]fluoro-L-DOPA metabolism in
living human brain: A comparison of six analytical methods. J Cereb Blood Flow Metab 13: 57-69.
79. Gjedde A, Kuwabara H (1993) Absent recruitment of capillaries in brain tissue recovering from stroke. Acta Neurochir
57: 35-40.
80. Cumming P, L´eger GC, Kuwabara H, Gjedde A (1993) Pharmacokinetics of plasma 6-[18F]fluoro-L-3,4-dihydroxyphenylalanine
([18F]FDOPA) in humans. J Cereb Blood Flow Metab 13: 668-675.
81. Guttman M, L´eger G, Reches A, Evans A, Kuwabara H, Cedarbaum JM, Gjedde A (1993) Administration of the new
comt inhibitor OR-611 increases striatal uptake of fluorodopa. Movement Disorders 8: 298-304.
82. Gjedde A, L´eger G, Cumming P, Yasuhara Y, Evans AC, Guttman M, Kuwabara H (1993) Striatal L-DOPA decarboxylase
activity in Parkinson’s disease in vivo: Implications for the regulation of dopamine synthesis. J Neurochem
61: 1538-1541.
83. Takada A, Grdiˇsa N, Diksic M, Gjedde A, Yamamoto YL (1993) Rapid steady-state analysis of blood-brain transfer
of L-tryptophan in rat, with special reference to the plasma protein binding. Neurochem Int 23: 351-359.
84. Cumming P, Gjedde A (1993) Kinetics of the uptake of [3H]paroxetine in the rat brain. Synapse 15: 124-129.
85. Cumming P, Vincent S, Gjedde A (1994) Histamine H3 binding sites in the rat brain: Localization in the nucleus
solitary tract. Brain Res 641: 198-202.
86. Cumming P, Gjedde A (1994) Subclasses of histamine H3 binding sites in the rat brain. Brain Res 641: 203-207.
87. Waaben J, Sørensen HR, Andersen UL, Gefke K, Lund J, Aggestrup S, Laursen H, Gjedde A (1994) Brain damage
following low flow cardiopulmonary bypass in pigs. Eur J Cardio-Thoracic Surg 8: 91-96.
88. Waaben J, Sørensen HR, Andersen UL, Gefke K, Lund J, Aggestrup S, Laursen H, Gjedde A (1994) Arterial line
filtration protects brain microcirculation during cardiopulmonary bypass. J Thorac Cardiovasc Surg 107: 1030-1035.
89. Cumming P, Kuwabara H, Gjedde A (1994) Kinetic analysis of 6-[18F]fluoro-L-dihydroxyphenyl-alanine ([18F]DOPA)
metabolism in the rat. J Neurochem 63: 1675-1682.
90. Cumming P, Venkatachalam TK, Rajagopal S, Diksic M, Gjedde A (1994) Kinetics of the cerebral uptake of -
[14C]methyl-para-tyrosine in the rat. Synapse 17: 125-128.
91. Zeitouni AG, Yamamoto YL, Black M, Gjedde A (1994) Functional imaging of head and neck tumors using positron
emission tomography. J Otolaryngol 23: 77-80.
92. Berger R, Gjedde A, Heck J, M¨uller E, Krieglstein J, Jensen A (1994) Extension of the 2-deoxyglucose method to the
fetus in utero: Theory and normal values for the cerebral glucose consumption in fetal guinea pigs. J Neurochem 63:
271-279.
93. Coghill RC, Talbot JD, Evans AC, Meyer E, Gjedde A, Bushnell MC, Duncan GH (1994) Distributed processing of
pain and vibration by the human brain. J Neuroscience 14: 4095-4108.
94. Cumming P, Lalibert´e C, Gjedde A (1994) Distribution of histamine H3 binding in forebrain of mouse and guinea
pig. Brain Res 664: 276-279.
95. Reith J, Benkelfat C, Sherwin A, Yasuhara Y, Kuwabara H, Andermann F, Bachneff S, Cumming P, Diksic M, Dyve S,
Etienne P, Evans A, Lal S, Shevell M, Savard G,Wong D, Chouinard G, Gjedde A (1994) Elevated dopa decarboxylase
activity in living brain of patients with psychosis. Proc Nat Acad Sci USA 91: 11651-11654.
96. Benkelfat C, Bradwejn J, Meyer E, Ellenbogen M, Milot S, Gjedde A, Evans A (1995) Functional neuroanatomy of
CCK4-induced anxiety in normal healthy volunteers. Am J Psychiat 152: 1180-1184.
97. Cumming P, Ase A, Diksic M, Harrison J, Kuwabara H, Laliberte C, Gjedde A (1995) Metabolism and blood-brain
clearance of L-3,4-dihydroxy-[3H]phenylalanine ([3H]DOPA) and 6-[18F]fluoro-L-DOPA in the rat. Biochem Pharmacol
50: 943-946.
98. Cumming P, Kuwabara H, Ase A, Gjedde A (1995) Regulation of DOPA decarboxylase activity in brain of living rat.
J Neurochem 65: 1381-1390.
99. Dyve S, Yang Y-J, McHugh M, Gjedde A, Pappius H (1995) Effect of injury on the bi-affinity 1-adrenoceptor binding
in the rat brain in vivo. Synapse 19: 88-96
2 PEER-REVIEWED REPORTS OF ORIGINAL FINDINGS 6
100. Kuwabara H, Cumming P, Yasuhara Y, Leger G, Guttman M, Diksic M, Evans AC, Gjedde A (1995) Regional striatal
DOPA transport and decarboxylation activity in Parkinson’s disease. J Nucl Med 36: 1226-1231.
101. Wang GJ, Volkow ND, Logan J, Fowler JS, Schlyer D, MacGregor RR. Hitzemann RJ, Gjedde A, Wolf AP (1995)
Serotonin 5-HT2 receptor availability in chronic cocaine abusers. Life Sciences 56: PL299-303.
102. Ohta S, Meyer E, Fujita H, Reutens DC, Evans A, Gjedde A (1996) Cerebral [O-15]water clearance in humans
determined by PET. I. Theory and normal values. J Cereb Blood Flow Metab 16: 765-780.
103. Murase K, Kuwabara H, Yasuhara Y, Evans AC, Gjedde A (1996) Mapping of change in cerebral glucose utilization
using fluorine-18 fluorodeoxyglucose double injection and the constrained weighted-integration method. IEEE Transact
Med Imag 15: 824-835.
104. Reutens DC, McHugh MD, Toussaint PJ, Evans AC, Gjedde A, Meyer E. Stewart DJ (1997) l-Arginine infusion
increases basal but not activated cerebral blood flow in humans. J Cereb Blood Flow Metab 17: 309-315
2.5 Aarhus 1994-2008
105. Gee AD, Smith DF, Gjedde A (1995) The synthesis of [O-methyl-11C]venlafaxine: A potential tracer of the 5-HT
reuptake site. J Labelled Comp Radiopharm 37: 309-310.
106. Wong DF, Harris JC, Naidu S, Yokoi F, Marenco S, Dannals RF, Ravert HT, Yaster M, Evans A, Rousset O, Bryan
RN, Gjedde A, Kuhar MJ, Breese GR (1996) Dopamine transporters are markedly reduced in Lesch-Nyhan Disease
in vivo. Proc Nat Acad Sci USA 93: 5539-5543.
107. Berger R, Gjedde A, Rischke R, M¨uller E, Heck J, Krieglstein J, Jensen A (1996) Local cerebral glucose utilization
in fetal guinea pigs at 0.75 gestation. Eur J Obstet Gynecol Reprod Biol 66: 175-178.
108. Møller N, Frystyk J, Skjærbæk C, Pedersen HB, Christensen C, Schmitz O, Gee A, Gjedde A, Zapf J, Ørskov H (1996)
Systemic and regional tumour metabolism in a patient with non-islet cell tumour hypoglycemia - role of increased levels
of free insulin-like growth factors. Diabetologia 39: 1534-1535.
1997
109. Bøtker HE, B¨ottcher M, Schmitz O, Gee A, Hansen SB, Cold GE, Nielsen TT, Gjedde A (1997) Glucose uptake
and lumped constant variability in normal human hearts determined with [F-18]fluorodeoxyglucose. J Nucl Cardiol 4:
125-132
110. Wong DF, Young D, Wilson PD, Meltzer CC, Gjedde A (1997) Quantification of neuroreceptors in the living human
brain .3. D-2-like dopamine receptors - theory, validation, and changes during normal aging. J Cereb Blood Flow Metab
17: 316-330
111. Wong DF, Pearlson GD, Tune LE, Young LT, Meltzer CC, Dannals RF. Ravert HT, Reith J, Kuhar MJ, Gjedde A
(1997) Quantification of neuroreceptors in the living human brain .4. effect of aging and elevations of D-2-like receptors
in schizophrenia and bipolar illness. J Cereb Blood Flow Metab 17: 331-342
112. Berger R, Gjedde A, Hargarter L, Hargarter S, Krieglstein J, Jensen A (1997) Regional cerebral glucose utilization in
immature fetal guinea pigs during maternal isocapnic hypoxemia. Pediat Res 42: 311-316
113. Wong DF, Singer HS, Brandt J, Shaya E, Chen C, Brown J, Kimball AW. Gjedde A, Dannals RF, Ravert HT, Wilson
PD, Wagner HN (1997) D2-like dopamine receptor density in tourette syndrome measured by pet. J Nucl Med 38:
1243-1247
114. Smith DF, Jensen PN, Gee AD, Hansen SB, Danielsen E, Andersen F. Saiz PA, Gjedde A (1997) PET neuroimaging
with [C-11]venlafaxine - serotonin uptake inhibition, biodistribution and binding in living pig brain. Eur Neuropsy-
chopharmacol 7: 195-200
115. Johannsen P, Jakobsen JK, Gjedde A, Christensen T Gulmann NC, Abelskov KE, Ehlers L (1997) [A clinic for the
study of dementia — 110 consecutive patients] Ugeskr Laeger 159: 1246-1251
116. Cumming P, Ase A, Laliberte C, Kuwabara H,Gjedde A (1997) In vivo regulation of DOPA decarboxylase by dopamine
receptors in rat brain. J Cereb Blood Flow Metab 17: 1254-1260.
117. Johannsen P. Jakobsen J. Bruhn P. Hansen SB. Gee A. Stødkilde-Jorgensen H. Gjedde A. (1997) Cortical sites of
sustained and divided attention in normal elderly humans Neuroimage. 6: 145-155.
118. Deep P. Gjedde A. Cumming P. (1997) On the accuracy of an [f-18]fdopa compartmental model - evidence for vesicular
storage of [f-18]fluorodopamine in vivo J Neurosci Meth 76: 157-165
119. Deep P. Kuwabara H. Gjedde A. Cumming P. (1997) The kinetic behaviour of [H-3]dopa in living rat brain investigated
by compartmental modelling of static autoradiograms. J Neurosci Meth 78: 157-168
120. Gee AD. Moldt P. Gjedde A. (1997) The labelling of a novel tropane derivative [C-11]NS 2214 (BMS-204756) - an
inhibitor of the dopamine transporter. J Label Comp & Radiopharm 39: 959-972
121. Poulsen PH. Smith DF. Ostergaard L. Danielsen EH. Gee A. Hansen SB. Astrup J. Gjedde A (1997) In vivo estimation
of cerebral blood flow, oxygen consumption and glucose metabolism in the pig by [o-15]water injection, [o-15]oxygen
inhalation and dual injections of [F-18]fluorodeoxyglucose. J Neurosci Meth 77: 199-209
2 PEER-REVIEWED REPORTS OF ORIGINAL FINDINGS 7
1998
122. Reutens DC, Gjedde A, Meyer E (1998) Regional lumped constant differences and asymmetry in fluorine-18-FDGuptake
in temporal lobe epilepsy.J Nucl Med 39: 176-180.
123. Cumming P, Gjedde A (1998) Compartmental analysis of dopa decarboxylation in living brain from dynamic positron
emission tomograms. Synapse (New York) 29: 37-61.
124. Ostergaard L, Smith DF, Vestergaard-Poulsen P, Hansen SB, Gee AD, Gjedde A, Gyldensted C (1998) Absolute
cerebral blood flow and blood volume measured by magnetic resonance imaging bolus tracking: comparison with
positron emission tomography values. J Cereb Blood Flow Metab 18: 425-432
125. Reith J, Cumming P, Gjedde A (1998) Enhanced [3H]DOPA and [3H]dopamine turnover in striatum and frontal
cortex in vivo linked to glutamate receptor antagonism. J Neurochem 70: 1979-1985
126. Cumming P, Ase A, Kuwabara H, Gjedde A, (1998) [H-3]Dopa formed from [h-3]tyrosine in living rat brain is not
committed to dopamine synthesis, J Cereb Blood Flow Metab 18: 491-499
127. Pedersen JR, Johannsen P, Bak CK, Kofoed B, Saermark K, Gjedde A (1998) Origin of Human Motor Readiness
Field Linked to Left Middle Frontal Gyrus by MEG and PET. Neuroimage 8: 214-220
128. Ostergaard L, Johannsen P, Host-Poulsen P Vestergaard-Poulsen P; Asboe H, Gee AD, Hansen SB, Cold GE, Gjedde
A, Gyldensted C. (1998) Cerebral blood flow measurements by magnetic resonance imaging bolus tracking: comparison
with [(15)O]H2O positron emission tomography in humans. J Cereb Blood Flow Metab 18: 935-940
129. L´eger G, Gjedde A, Kuwabara H, Guttman M, Cumming P (1998) Effect of catechol-O-methyltransferase inhibition
on brain uptake of [18F]fluorodopa: Implications for compartmental modelling and clinical usefulness. Synapse 30:
351-361.
130. Svensson P, Johannsen P, Jensen TS, Arendt-Nielsen L, Nielsen J, Stødkilde-Jørgensen H, Gee AD, Hansen SB, Gjedde
A (1998) Cerebral blood flow changes evoked by two levels of painful tonic and phasic heat stimulation: A positron
emission tomography study. Eur J Pain 2: 95-107
131. Vafaee M, Meyer E, Marrett S, Evans AC, Gjedde A (1998) Increased oxygen consumption in human visual cortex:
Response to visual stimulation. Acta Neurol Scand 98: 85-89.
1999
132. Ptito M, Johannsen P, Faubert J, Gjedde A (1999) Activation of human extrageniculostriate pathways after damage
to area V1.Neuroimage 9: 97-107
133. Ohta S, Reutens DC, Gjedde A (1999) Brief vibrotactile stimulation does not increase cortical oxygen consumption
when measured by single inhalation of positron emitting oxygen. J Cereb Blood Flow Metab 19: 260-265
134. Fujita H, Kuwabara H, Reutens DC, Gjedde A (1999) Oxygen consumption of cerebral cortex fails to increase during
continued vibrotactile stimulation. J Cereb Blood Flow Metab 19: 266-271
135. Vafaee MS, Meyer E, Marrett S, Paus T, Evans AC, Gjedde A. (1999) Frequency-dependent changes in cerebral
metabolic rate of oxygen during activation of human visual cortex. J Cereb Blood Flow Metab 19: 272-277
136. Ptito M, Dalby M, Gjedde A. (1999) Visual field recovery in a patient with bilateral occipital lobe damage. Acta
Neurol Scand 99: 252-254
137. Cumming P, Reith J, Gjedde A (1999) Cocaine withdrawal and the cerebral influx of [18F]fluoro-L-DOPA (FDOPA).
Neuropsychopharmacology 20: 395-398
138. Smith DF, Gee AD, Hansen SB, Moldt P, Nielsen EO, Scheel-Kruger J, Gjedde A (1999) Uptake and distribution of
a new SSRI, NS2381, studied by PET in living porcine brain. Eur Neuropsychopharmacol 9: 351-359
139. Danielsen EH, Smith DF, Gee AD, Venkatachalam TK Hansen SB, Hermansen F, Gjedde A, Cumming P (1999)
Cerebral 6-[(18)F]fluoro-L-DOPA (FDOPA) metabolism in pig studied by positron emission tomography. Synapse 33:
247-258
140. Borbely K, Brooks RA, Wong DF, Burns RS, Cumming P, Gjedde A, Di Chiro G (1999) NMSP binding to dopamine
and serotonin receptors in MPTP-induced parkinsonism: relation to dopa therapy. Acta Neurol Scand 100: 42-52
141. Bøtker HE, Goodwin GW, Holden JE, Doenst T, Gjedde A, Taegtmeyer H (1999) Myocardial glucose uptake measured
with fluorodeoxyglucose: a proposed method to account for variable lumped constants. J Nucl Med 40: 1186-1196
142. Mirz F, Pedersen CB, Ishizu K, Johannsen P, Ovesen T, Stødkilde-Jørgensen H, Gjedde A (1999) Positron emission
tomography of cortical centers of tinnitus. Hear Res 134: 133-144.
143. Wiggers H, B¨ottcher M, Nielsen TT, Gjedde A, Bøtker HE (1999) Measurement of myocardial glucose uptake in patients
with ischemic cardiomyopathy: application of a new quantitative method using regional tracer kinetic information.
J Nucl Med 40: 1292-300
144. Johannsen P, Jakobsen J, Bruhn P, GjeddeA (1999) Cortical responsesto sustained and divided attention in Alzheimer’s
disease. Neuroimage 10: 269-281
2 PEER-REVIEWED REPORTS OF ORIGINAL FINDINGS 8
145. Mirz F, Ovesen T, Ishizu K, Johannsen P, Madsen S, Gjedde A, Pedersen CB (1999) Stimulus-dependent central
processing of auditory stimuli: a PET study. Scand Audiol 28: 161-169.
146. Cumming P, Yokoi F, Chen A, Deep P, Dagher A, Reutens D, Kapczinski F, Wong DF, Gjedde A (1999) Pharmacokinetics
of radiotracers in human plasma during positron emission tomography. Synapse 34: 124-134
147. Deep P, Dagher A, Sadikot A, Gjedde A, Cumming P (1999) Stimulation of dopa decarboxylase activity in striatum
of healthy human brain secondary to NMDA receptor antagonism with a low dose of amantadine. Synapse 34: 313-318
2000
148. Mirz F, Gjedde A, Stødkilde-Jørgensen H, Pedersen CB (2000) Functional brain imaging of tinnitus-like perception
induced by aversive auditory stimuli. NeuroReport 11: 633-637
149. Vafaee MS, Gjedde A (2000) Model of blood-brain transfer of oxygen explains non-linear flow-metabolism coupling
during stimulation of visual cortex. J Cereb Blood Flow Metab 20: 747-754.
150. Pedersen CB, Mirz F, Ovesen T, Ishizu K, Johannsen P, Madsen S, Gjedde A (2000) Cortical centres underlying
auditory temporal processing in humans: a PET study. Audiology 39: 30-37.
151. Danielsen EH, Cumming P, Andersen F, Bender D, Brevig T, Falborg L, Gee A, Gillings NM, Hansen SB, Hermansen
F, Johansen J, Johansen TE, Dahl-Jørgensen A, Jørgensen HA, Meyer M, Munk O, Pedersen EB, Poulsen PH, Rodell
AB, Sakoh M, Simonsen CZ, Smith DF, Sørensen JC, stergard L, Zimmer J, Gjedde A(2000) The DaNeX study of
embryonic mesencephalic, dopaminergic tissue grafted to a minipig model of Parkinson’s disease: Preliminary findings
of effect of MPTP poisoning on striatal dopaminergic markers. Cell Transplant 9: 247-259.
152. Bøtker HE, Wiggers H, Bøttcher M, Christiansen JS, Nielsen TT, Gjedde A, Schmitz O (2000) Short-term effects of
growth hormone on myocardial glucose uptake in healthy humans. Am J Physiol (EndocrinolMetab) 278: E1053-E1059.
153. Rousset OG, Deep P, Kuwabara H, Evans AC, Gjedde A, Cumming P (2000) Effect of partial volume correction
on estimates of the influx and cerebral metabolism of 6-[(18)F]fluoro-L-dopa studied with PET in normal control and
Parkinson’s disease subjects. Synapse 37: 81-89.
154. Kupers RC, Gybels JM, Gjedde A (2000) Positron emission tomography study of a chronic pain patient successfully
treated with somatosensory thalamic stimulation. Pain 87: 295-302.
155. Ishizu K, Smith DF, Bender D, Danielsen E, Hansen SB, Wong DF, Cumming P, Gjedde A (2000) Positron emission
tomography of radioligand binding in porcine striatum in vivo: Haloperidol inhibition linked to endogenous ligand
release. Synapse 38: 87-101.
156. Sakoh M, Rohl L, Gyldensted C, Gjedde A, Ostergaard L (2000) Cerebral blood flow and blood volume measured by
magnetic resonance imaging bolus tracking after acute stroke in pigs: comparison with [(15)O]H(2)O positron emission
tomography. Stroke 31: 1958-1964.
157. Mirz F, Gjedde A, Ishizu K, Pedersen CB (2000) Cortical networks subserving the perception of tinnitus–a PET
study. Acta Otolaryngol Suppl. 543: 241-243.
158. Johannsen P, Jakobsen J, Gjedde A (2000) Statistical maps of cerebral blood flow deficits in Alzheimer’s disease. Eur
J Neurol 7: 385-392.
159. Vafaee MS, Meyer E, Gjedde A (2000) Impaired activation of oxygen consumption and blood flow in visual cortex of
patients with mitochondrial encephalomyopathy. Ann Neurol 48: 676-679.
160. Sakoh M, Ostergaard L, Rohl L, Smith DF, Simonsen CZ, Sorensen JC, Poulsen PV, Gyldensted C, Sakaki S, Gjedde
A (2000) Relationship between residual cerebral blood flow and oxygen metabolism as predictive of ischemic tissue
viability: sequential multitracer positron emission tomography scanning of middle cerebral artery occlusion during the
critical first 6 hours after stroke in pigs. J Neurosurg 93: 647-657.
2001
161. Danielsen EH, Smith D, Hermansen F, Gjedde A, Cumming P (2001) Acute neuroleptic stimulates DOPA decarboxylase
in porcine brain in vivo. Synapse 41: 172-175
162. Cumming P, Danielsen EH, Vafaee M, Falborg L, Steffensen E, Sorensen JC, Gillings N, Bender D, Marthi K, Andersen
F, Munk O, Smith D, Moller A, Gjedde A (2001) Normalization of markers for dopamine innervation in striatum of
MPTP-lesioned miniature pigs with intrastriatal grafts. Acta Neurol Scand 103: 309-315
163. Smith DF, Bender D, Marthi K, Cumming P, Hansen SB, Peters D, Ostergaard Nielsen E, Scheel-Kruger J, Gjedde
A (2001) Synthesis and evaluation of racemic.... Nucl Med Biol 28: 265-270
164. Gjedde A, Wong DF (2001) Quantification of neuroreceptors in living human brain. V. Endogenous neurotransmitter
inhibition of haloperidol binding in psychosis. J Cereb Blood Flow Metab 21: 982-994.
165. Smith DF, Hansen SB, Ostergaard L, Gee AD, Danielsen E, Ishizu K, Bender D, Poulsen PH, Gjedde A (2001)
[14C]Serotonin uptake and [O-methyl-11C]venlafaxine kinetics in porcine brain. Nucl Med Biol 28: 633-638.
2 PEER-REVIEWED REPORTS OF ORIGINAL FINDINGS 9
166. Sakoh M, Ostergaard L, Gjedde A, Rohl L, Vestergaard-Poulsen P, Smith DF, Le Bihan D, Sakaki S, Gyldensted C
(2001) Prediction of tissue survival after middle cerebral artery occlusion based on changes in the apparent diffusion of
water. J Neurosurg 95: 450-458.
167. Danielsen EH, Smith DF, Andersen F, Gee AD, Bender D, Hansen SB, Hermansen F, Ostergaard L, Cumming P,
Gjedde A (2001) FDOPA metabolism in the adult porcine brain: influence of tracer circulation time and VOI selection
on estimates of striatal DOPA decarboxylation. J Neurosci Methods 111: 157-168.
168. Videbech P, Ravnkilde B, Pedersen AR, Egander A, Landbo B, Rasmussen NA, Andersen F, Stodkilde-Jorgensen H,
Gjedde A, Rosenberg R (2001) The Danish PET/depression project: PET findings in patients with major depression.
Psychol Med 31: 1147-1158.
169. Watanabe H, Andersen F, Simonsen CZ, Evans SM, Gjedde A, Cumming P (2001) MR-based statistical atlas of the
Gottingen minipig brain. Neuroimage 14: 1089-1096.
170. Ptito M, Kupers R, Faubert J, Gjedde A (2001) Cortical representation of inward and outward radial motion in man.
Neuroimage 14: 1409-1415.
171. Witting N, Kupers RC, Svensson P, Arendt-Nielsen L, Gjedde A, Jensen TS (2001) Experimental brush-evoked
allodynia activates posterior parietal cortex. Neurology 57: 1817-1824.
172. Gjedde A, Marrett S (2001) Glycolysis in neurons, not astrocytes, delays oxidative metabolism of human visual cortex
during sustained checkerboard stimulation in vivo. J Cereb Blood Flow Metab 21: 1384-1392.
2002
173. Marthi K, Bender D, Gjedde A, Smith DF (2002) [11C]Mirtazapine for PET neuroimaging: Radiosynthesis and initial
evaluation in the living porcine brain. Eur Neuropsychopharmacol 12: 427-432.
174. Ravnkilde B, Videbech P, Rosenberg R, Gjedde A, Gade A (2002) Putative tests of frontal lobe function: A PET-study
of brain activation during Stroop’s test and Verbal Fluency. J Clin Exp Neuropsychol 24: 534-547.
175. Videbech P, Ravnkilde B, Pedersen TH, Hartvig H, Egander A, Clemmensen K, Rasmussen NA, Andersen F, Gjedde
A, Rosenberg R (2002) The Danish PET/depression project: clinical symptoms and cerebral blood flow. A regions-ofinterest
analysis. Acta Psychiatr Scand 106: 35-44.
176. Cumming P, Wong DF, Gillings N, Hilton J, Scheffel U, Gjedde A(2002) Specific binding of [11C]raclopride and
N-[(3)H]propyl-norapomorphine to dopamine receptors in living mouse striatum: occupancy by endogenous dopamine
and guanosine triphosphate-free G protein. J Cereb Blood Flow Metab 22: 596-604.
177. Gjedde A (2002) Cerebral blood flow change in arterial hypoxemia is consistent with negligible oxygen tension in
brain mitochondria. Neuroimage 17: 1876-1881.
178. Dall AM, Danielsen EH, Sorensen JC, Andersen F, Moller A, Zimmer J, Gjedde A, Cumming P (2002) Quantitative
[18F]fluorodopa/PET and histology of fetal mesencephalic dopaminergic grafts to the striatum of MPTP-poisoned
minipigs. Cell Transplant 11: 733-746.
2003
179. Rasmussen M, Poulsen PH, Treiber A, Delahaye S, Tankisi A, Cold GE, Therkelsen K, Gjedde A, Astrup J (2003)
No influence of the endothelin receptor antagonist bosentan on basal and indomethacin-induced reduction of cerebral
blood flow in pigs. Acta Anaesthesiol Scand 47: 200-207.
180. Geday J, Gjedde A, Boldsen AS, Kupers R (2003) Emotional valence modulates activity in the posterior fusiform
gyrus and inferior medial prefrontal cortex in social perception. Neuroimage 18: 675-684.
181. Gr¨under G, Vernaleken I, Muller MJ, Davids E, Heydari N, Buchholz HG, Bartenstein P, Munk OL, Stoeter P, Wong
DF, Gjedde A, Cumming P (2003). Subchronic haloperidol downregulates dopamine synthesis capacity in the brain
of schizophrenic patients in vivo. Neuropsychopharmacology 28: 787-794.
182. Videbech P, Ravnkilde B, Kristensen S, Egander A, Clemmensen K, Rasmussen NA, Gjedde A, Rosenberg R (2003)
The Danish PET/depression project: poor verbal fluency performance despite normal prefrontal activation in patients
with major depression. Psychiatry Res 123: 49-63.
183. Ptito M, Faubert J, Gjedde A, Kupers R (2003) Separate neural pathways for contour and biological-motion cues in
motion-defined animal shapes. Neuroimage 19: 246-252.
184. Fortin A, Faubert J, Ptito A, Gjedde A, Kupers R, Ptito M (2003) Stereoscopic processing in the human brain as a
function of binocular luminance rivalry. Neuroreport 14: 1163-1166.
185. Cumming P, Gillings NM, Jensen SB, Bjarkam C, Gjedde A (2003) Kinetics of the uptake and distribution of the
dopamine D(2,3) agonist (R)-N-[1-(11)C]n-propylnorapomorphine in brain of healthy and MPTP-treated G¨ottingen
miniature pigs. Nucl Med Biol 30: 547-553.
186. Cumming P, Rosa-Neto P, Watanabe H, Smith D, Bender D, Clarke PB, Gjedde A (2003) Effects of acute nicotine
on hemodynamics and binding of [11C]raclopride to dopamine D2,3 receptors in pig brain. Neuroimage 19: 1127-1136.
2 PEER-REVIEWED REPORTS OF ORIGINAL FINDINGS 10
187. Sakoh M, Gjedde A (2003). Neuroprotection in hypothermia linked to redistribution of oxygen in brain. Am J Physiol
285: H17-H25.
188. Ravnkilde B, Videbech P, Clemmensen K, Egander A, Rasmussen NA, Gjedde A, Rosenberg R, Gade A (2003) The
Danish PET/depression project: cognitive function and regional cerebral blood flow. Acta Psychiatr Scand 108: 32-40.
189. Arnfred SM, Lind NM, Moustgaard A, Hansen AK, Gjedde A (2003) Minipig negative slow wave demonstrates
target/nontarget differences in P300 paradigm. Neuroimage 20: 587-590.
190. Borbely K, Gjedde A, Nyary I, Czirjak S, Donauer N, Buck A (2003) Speech activation of language dominant hemisphere:
a single-photon emission computed tomography study. Neuroimage 20: 987—994.
2004
191. Vafaee MS, Gjedde A (2004) Spatially dissociated flow-metabolism coupling in brain activation. Neuroimage 21:
507-515.
192. Vafaee MS, stergaard K, Sunde N, Gjedde A, Dupont E, Cumming P (2004) Focal changes of oxygen consumption in
cerebral cortex of patients with Parkinson’s disease during subthalamic stimulation. Neuroimage 22: 966-974.
193. Arnfred SM, Lind NM, Gjedde A, Hansen AK (2004) Scalp recordings of mid-latency AEP and auditory gating in
the Gottingen minipig: a new animal model in information processing research. Int J Psychophysiol 52: 267-275.
194. Videbech P, Ravnkilde B, Gammelgaard L, Egander A, Clemmensen K, Rasmussen NA, Gjedde A, Rosenberg R
(2004) The Danish PET/depression project: performance on Stroop’s test linked to white matter lesions in the brain.
Psychiatry Res 130: 117-130.
195. Lou HC, Rosa P, Pryds O, Karrebaek H, Lunding J, Cumming P,Gjedde A (2004) ADHD: Increased dopamine receptor
availability linked to attention deficit and low neonatal cerebral blood flow. Dev Med Child Neurol 46: 179-183.
196. Rosa-Neto P, Gjedde A, Olsen AK, Jensen SB, Munk OL, Watanabe H, Cumming P (2004) MDMA-evoked changes
in [(11)C]raclopride and [(11)C]NMSP binding in living pig brain. Synapse 53: 222-233.
197. Rosa-Neto P, Olsen AK, Gjedde A, Watanabe H, Cumming P (2004) MDMA-evoked changes in cerebral blood flow
in living porcine brain: Correlation with hyperthermia. Synapse 53: 214-221.
198. Kumakura Y, Danielsen EH, Reilhac A, Gjedde A, Cumming P (2004) Levodopa effect on [18F]fluorodopa influx to
brain: normal volunteers and patients with Parkinson’s disease. Acta Neurol Scand 110: 188-195.
199. Schl¨unzen L, Vafaee MS, Cold GE, Rasmussen M, Nielsen JF, Gjedde A (2004) Effects of subanaesthetic and anaesthetic
doses of sevoflurane on regional cerebral blood flow in healthy volunteers. A positron emission tomographic
study. Acta Anaesthesiol Scand 48: 1268-1276.
200. Kupers RC, Fortin A, Astrup J, Gjedde A, Ptito M (2004) Recovery of anterograde amnesia in a case of craniopharyngioma.
Arch Neurol 61: 1948-1952
2005
201. Vuust P, Pallesen KP, Bailey C, van Zuijen TL, Gjedde A, Roepstorff A, stergaard L (2005) To musicians, the message
is in the meter. Pre-attentive neuronal responses to incongruent rhythm are left-lateralized in musicians. Neuroimage
24: 560-564.
202. Gjedde A, Johannsen P, Cold GE, stergaard L (2005) Cerebral metabolic response to low blood flow: Possible role of
cytochrome oxidase inhibition. J Cereb Blood Flow Metab 25: 1183-1196.
203. Lind NM, Olsen AK, Moustgaard A, Jensen SB, Jaboksen S, Hansen AK, Arnfred AM, Hemmingsen RP, Gjedde A,
Cumming, P (2005) Mapping the amphetamine-evoked dopamine release in the brain of the Gttingen minipig. Brain
Res Bull 65: 1-9.
204. Ptito M, Moesgaard SM, Gjedde A, Kupers R (2005) Crossmodal plasticity revealed by electrotactile stimulation of
the tongue in the congenitally blind. Brain 128: 606-614.
205. Rosa-Neto P, Lou HC, Cumming P, Pryds O, Karrebaek H, Lunding J, Gjedde A (2005) Methylphenidate-evoked
changes in striatal dopamine correlate with inattention and impulsivity in adolescents with attention deficit. Neuroimage
25: 868-876.
206. Kumakura Y, Vernaleken I, Gr¨under G, Bartenstein P, Gjedde A, Cumming P (2005) PET studies of net blood-brain
clearance of FDOPA to human brain: Age-dependent decline of [18F]fluorodopamine storage capacity. J Cereb Blood
Flow Metab 25: 807-819.
207. Mortensen MV, Madsen S, Gjedde A (2005) Cortical responses to promontorial stimulation in postlingual deafness.
Hear Res 209: 32-41
208. Lind NM, Gjedde A, Moustgaard A, Olsen AK, Jensen SB, Jakobsen S, Arnfred SM, Hansen AK, Hemmingsen
RP, Cumming P (2005) Behavioral response to novelty correlates with dopamine receptor availability in striatum of
Gottingen minipigs. Behav Brain Res 164: 172-177.
209. Villeneuve MY, Kupers R, Gjedde A, Ptito M, Casanova C (2005) Pattern-motion selectivity in the human pulvinar.
Neuroimage 28: 474-480.
2 PEER-REVIEWED REPORTS OF ORIGINAL FINDINGS 11
210. Mortensen MV, Madsen S, Gjedde A (2005) Use of time differences in normal hearing–cortical processing of promontorial
stimuli. Hear Res 205: 94-101.
211. Jelsing J, Olsen AK, Cumming P,Gjedde A, Hansen AK, Arnfred S, Hemmingsen R, Pakkenberg B (2005) A volumetric
screening procedure for the Gottingen minipig brain. Exp Brain Res 162: 428-435.
212. Pallesen KJ, Brattico E, Bailey C, Korvenoja A, Koivisto J, Gjedde A, Carlson S (2005) Emotion processing of major,
minor, and dissonant chords: a functional magnetic resonance imaging study. Ann N Y Acad Sci 1060: 450-453.
2006
213. Kumakura Y, Gjedde A, Danielsen EH, Christensen S, Cumming P (2006) Dopamine storage capacity in caudate and
putamen of patients with early Parkinson’s disease: correlation with asymmetry of motor symptoms. J Cereb Blood
Flow Metab 26: 358-370
214. Mortensen MV, Mirz F, Gjedde A (2006) Restored speech comprehension linked to activity in left inferior prefrontal
and right temporal cortices in postlingual deafness. Neuroimage 31: 842-852.
215. Geday JA, stergaard K, Gjedde A (2006) Stimulation of the subthalamic nucleus inhibits emotional activation of the
fusiform gyrus. Neuroimage 33: 706-714.
216. Wong DF, Kuwabara H, Schretlen DJ, Bonson KR, Zhou Y, Nandi A, Brasic J, Kimes AS, Maris MA, Kumar A,
Contoreggi C, Links J, Ernst M, Rousset O, Zukin S, Grace AA, Rohde C, Jasinski DR, Gjedde A, London ED (2006)
Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving. Neuropsychophar-
macology 31: 2716-2727.
217. Kupers R, Fumal A, Maertens de Noordhout A, Gjedde A, Schoenen J, Ptito M (2006) TMS of the visual cortex
induces somatotopically organized qualia in blind subjects. Proc Nat Acad Sci (USA) 103: 13256-13260.
2007
218. Rasmussen P, Dawson EA, Nybo L, van Lieshout JJ, Secher N, Gjedde A (2007) Capillary oxygenation-level-dependent
(COLD) near-infrared spectrometry (NIRS) in frontal lobe of humans. J Cereb Blood Flow Metab 27: 1082-1093.
219. Johansen ML, Bak LK, Schousboe A, Iversen P, Sorensen M, Keiding S, Vilstrup H, Gjedde A, Ott P, Waagepetersen
HS (2007). The metabolic role of isoleucine in detoxification of ammonia in cultured mouse neurons and astrocytes.
Neurochem Int. 50: 1042-1051.
220. Møller M, Frandsen J, Andersen G, Gjedde A, Vestergaard-Poulsen P, stergaard L (2007). Dynamic changes in
corticospinal tracts after stroke detected by fibretracking. J Neurol Neurosurg Psychiatry 78: 587-592.
221. Møller M, Jakobsen S, Gjedde A (2007). Parametric and Regional Maps of Free Serotonin 5HT(1A) Receptor Sites
in Human Brain as Function of Age in Healthy Humans. Neuropsychopharmacology 32: 1707-1714.
222. Møller M, Andersen G, Gjedde A (2007). Serotonin 5HT1A receptor availability and pathological crying after stroke.
Acta Neurol Scand. 116: 83-90.
223. Geday J, Kupers R, Gjedde A (2007). As Time Goes By: Temporal Constraints on Emotional Activation of Inferior
Medial Prefrontal Cortex. Cereb Cortex 17: 2753-2759.
2008
224. Hall NM, Gjedde A, Kupers R (2008) Neural mechanisms of voluntary and involuntary recall: A PET study. Behav
Brain Res 186: 261-272.
225. Ptito M, Fumal A, de Noordhout AM, Schoenen J, Gjedde A, Kupers R (2008). TMS of the occipital cortex induces
tactile sensations in the fingers of blind Braille readers. Exp Brain Res. 184: 193-200.
226. Wong DF, Braic JR, Singer HS, Schretlen DJ, Kuwabara H, Zhou Y, Nandi A, Maris MA, Alexander M, Ye W, Rousset
O, Kumar A, Szabo Z, Gjedde A, Grace AA (2008) Mechanisms of dopaminergic and serotonergic neurotransmission in
Tourette syndrome: Clues from an in vivo neurochemistry study with PET. Neuropsychopharmacology 33: 1239-1251.
227. Lerche S, Brock B, Rungby J, Bøtker HE, Møller N, Rodell A, Bibby BM, Holst JJ, Schmitz O, Gjedde A (2008)
Glucagon-like-peptide-1 inhibits blood-brain glucose transfer in humans. Diabetes 57: 325-331.
228. Borghammer P, Jonsdottir KY, Cumming P, Ostergaard K, Vang K, Ashkanian M, Vafaee M, Iversen P, Gjedde A
(2008) Normalization in PET group comparison studies–the importance of a valid reference region. Neuroimage 40:
529-540.
229. Ashkanian M, Borghammer P, Gjedde A, Ostergaard L, Vafaee M (2008) Improvement of brain tissue oxygenation by
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